Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions; human homolog EIF2B1 can complement yeast null mutant [Source:SGD;Acc:S000001734]

Chromosome XI: 488,738-489,655 reverse strand.

This transcript has 1 exon, is annotated with 16 domains and features, is associated with 24 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKR026C Show transcript tableHide transcript table