5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; plays a key role in cell wall integrity (CWI) pathway; one of five related enzymes, which are active as heteromultimeric complexes; missense mutations in human homolog PRPS1 are associated with neuropathic Arts syndrome and Charcot-Marie Tooth (CMTX5) disease [Source:SGD;Acc:S000001664]

Chromosome XI: 107,316-108,599 forward strand.

This transcript has 1 exon, is annotated with 26 domains and features, is associated with 25 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKL181W Show transcript tableHide transcript table