Essential nuclear envelope/ER integral membrane protein; interacts and functions with Apq12p and Brr6p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, mRNA nuclear export and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; identified as a dosage suppressor of a temperature sensitive mutation in the major karyopherin, CRM1; homologous to Brr6p [Source:SGD;Acc:S000001078]

Chromosome VIII: 180,345-181,760 forward strand.

This transcript has 1 exon, is annotated with 17 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YHR036W Show transcript tableHide transcript table