Essential nuclear envelope integral membrane protein; interacts and functions with Apq12p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA nuclear export, and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; homologous to Brl1p [Source:SGD;Acc:S000003216]

Chromosome VII: 36,933-37,526 forward strand.

This transcript has 1 exon, is annotated with 13 domains and features, is associated with 22 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YGL247W Show transcript tableHide transcript table