Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate [Source:SGD;Acc:S000003092]

Chromosome VII: 274,780-276,714 reverse strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 61 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YGL124C Show transcript tableHide transcript table