Highly conserved negative regulator of RNA polymerase III; involved in tRNA processing and stability; inhibits tRNA degradation via rapid tRNA decay (RTD) pathway; binds N-terminal domain of Rpc160p subunit of Pol III to prevent closed-complex formation; regulated by phosphorylation mediated by TORC1, protein kinase A, Sch9p, casein kinase 2; localizes to cytoplasm during vegetative growth and translocates to nucleus and nucleolus under stress conditions [Source:SGD;Acc:S000002412]

Chromosome IV: 456,836-458,103 reverse strand.

This transcript has 2 exons, is annotated with 13 domains and features, is associated with 20 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDR005C Show transcript tableHide transcript table