S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; mammalian claspin homolog [Source:SGD;Acc:S000000566]

Chromosome III: 18,816-22,106 reverse strand.

This transcript has 1 exon, is annotated with 31 domains and features, is associated with 65 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YCL061C Show transcript tableHide transcript table