Saccharomyces cerevisiae Assembly and Gene Annotation

About Saccharomyces cerevisiae S288c

Saccharomyces cerevisiae is a species of yeast. The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes. It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology, much like Escherichia coli as the model bacterium. It is the microorganism which causes many common types of fermentation. S. cerevisiae cells are round to ovoid, 5–10 μm in diameter. It reproduces by budding.

Picture credit: Creative Commons Attribution 3.0 via Wikimedia Commons (Image source) Taxonomy ID 559292

(Text from Wikipedia.)

More information General information about this species can be found in Wikipedia

Assembly

The assembly provided on this site is the R64-1-1 assembly, imported from the Saccharomyces Genome Database (SGD).

Annotation

::: {#annotation} The protein-coding and non-coding gene model annotation was imported from the Saccharomyces Genome Database (SGD) in April 2018. This gene set is based on Liachko et al. 2013 [6], and contains 7036 protein-coding genes. Additionally, 91 transposable element genes (TE genes) that were previously annotated as protein-coding genes have now been correctly captured as TE genes. :::

Variation

The variation data provided by this site were imported from data provided by the Saccharomyces Genome Resequencing Project (SGRP).

References

1. A large-scale full-length cDNA analysis to explore the budding yeast transcriptome.
   Miura F, Kawaguchi N, Sese J, Toyoda A, Hattori M, Morishita S, Ito T. 2006. Proc. Natl. Acad. Sci. U.S.A.. 103:17846-17851.
2. Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing.
   Yassour M, Kaplan T, Fraser HB, Levin JZ, Pfiffner J, Adiconis X, Schroth G, Luo S, Khrebtukova I, Gnirke A et al. 2009. Proc. Natl. Acad. Sci. U.S.A.. 106:3264-3269.
3. Genetic and physical maps of Saccharomyces cerevisiae.
   Cherry JM, Ball C, Weng S, Juvik G, Schmidt R, Adler C, Dunn B, Dwight S, Riles L, Mortimer RK et al. 1997. Nature. 387:67-73.
4. Life with 6000 genes.
   Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M et al. 1996. Science. 274:546, 563-7.
5. Population genomics of domestic and wild yeasts.
   Liti G, Carter DM, Moses AM, Warringer J, Parts L, James SA, Davey RP, Roberts IN, Burt A, Koufopanou V et al. 2009. Nature. 458:337-341.
6. High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.
   Cubillos FA, Parts L, Salinas F, Bergstrm A, Scovacricchi E, Zia A, Illingworth CJ, Mustonen V, Ibstedt S, Warringer J et al. 2013. Genetics. 195:1141-1155.
7. The Reference Genome Sequence of Saccharomyces cerevisiae: Then and Now.
   Dietrich FS, Fisk DG, Binkley G, Balakrishnan R, Costanzo MC, Dwight SS, Hitz BC, Karra K, Nash RS, Weng S et al. 2013. G3 (Bethesda).
8. High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast.
   Liachko I, Youngblood RA, Keich U, Dunham MJ. 2013. Genome research.

Other data

• Mapping of probe sequences from the Affymetrix Yeast Genome 2.0 Array

• Mapping of probe sequences from the Affymetrix Yeast Genome S98 Array

• Predicted UTRs and transcribed regions from Yassour et al.

More information

General information about this species can be found in Wikipedia.