High-affinity copper transporter of plasma membrane; mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels; protein increases in abundance and relocalizes from nucleus to plasma membrane upon DNA replication stress; human homolog SLC31A1 can complement a yeast ctr1 ctr3 double deletion [Source:SGD;Acc:S000006328]
Chromosome XVI: 786,208-787,428 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 158 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CTR1 | YPR124W_mRNA | 1221 | 406aa | YPR124W | Protein coding | P49573 | - | Ensembl Canonical, |