ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics [Source:SGD;Acc:S000006139]
Chromosome XVI: 138,698-139,409 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 364 orthologues and 6 paralogues.