Vacuolar RNase of the T(2) family; relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; required for tRNA-specific translational pausing suring oxidative stress; promotes apoptosis under stress conditions and this function is independent of Rny1p catalytic activity [Source:SGD;Acc:S000006044]
Chromosome XVI: 317,641-318,945 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 394 orthologues and is a member of 1 Ensembl protein family.