Cytoplasmic NAD(+)-dependent protein deacetylase; deacetylation targets are primarily cytoplasmic proteins; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export [Source:SGD;Acc:S000005936]

Chromosome XVI: 525,810-526,883 reverse strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 387 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.

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