Alpha-isopropylmalate synthase II (2-isopropylmalate synthase); catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant; LEU9 has a paralog, LEU4, that arose from the whole genome duplication [Source:SGD;Acc:S000005634]
Chromosome XV: 523,027-524,841 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 411 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.