Protein required for flavinylation of Sdh1p; binds to Sdh1p and promotes FAD cofactor attachment, which is necessary for succinate dehydrogenase (SDH) complex assembly and activity; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma) [Source:SGD;Acc:S000005432]
Chromosome XV: 196,507-196,995 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 335 orthologues and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SDH5 | YOL071W_mRNA | 489 | 162aa | YOL071W | Protein coding | Q08230 | - | Ensembl Canonical, |