NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005429]

Chromosome XV: 200,368-201,879 reverse strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 346 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.

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