Dethiobiotin synthetase; catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; BIO3 and BIO4 were acquired by horizontal gene transfer (HGT) from bacteria; expression appears to be repressed at low iron levels [Source:SGD;Acc:S000005340]
Chromosome XIV: 733,356-734,069 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 23 orthologues and is a member of 2 Ensembl protein families.