Cytochrome c oxidase subunit; has a role in assembly of respiratory supercomplexes; similar to Rcf1p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; associates with the cytochrome c oxidase - cytochrome bc1 supercomplex; null mutant accumulates reactive oxygen species; member of the conserved hypoxia induced gene family; C. elegans homolog is functional in yeast [Source:SGD;Acc:S000005301]
Chromosome XIV: 664,270-664,944 forward strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 38 orthologues and is a member of 1 Ensembl protein family.