Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798]
HSP90
Chromosome XIII: 632,355-634,472 forward strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant), 390 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
HSC82 | YMR186W_mRNA | 2118 | 705aa | YMR186W | Protein coding | P15108 | - | Ensembl Canonical, |