Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE17 has a paralog, ADE16, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine [Source:SGD;Acc:S000004727]
Chromosome XIII: 507,502-509,280 reverse strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant), 356 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.