Major orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA5 has a paralog, URA10, that arose from the whole genome duplication [Source:SGD;Acc:S000004574]

PYR5

Chromosome XIII: 56,773-57,453 forward strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 173 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

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