DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells [Source:SGD;Acc:S000004526]

TST1

Chromosome XIII: 148,953-151,532 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 324 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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