Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1; upstream component for regulation through the small GTPase Rho5p; may form a complex with Lmo1p that acts as a GEF for Rho5p; interacts with Ino4p; cytoplasmic protein that relocates to mitochondria under oxidative stress; implicated in mitophagy; not an essential protein; DOCK proteins act as guanine nucleotide exchange factors [Source:SGD;Acc:S000004414]
Chromosome XII: 965,897-971,695 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 347 orthologues and is a member of 1 Ensembl protein family.