Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004413]
Chromosome XII: 965,090-965,560 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 190 orthologues and is a member of 1 Ensembl protein family.