Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome; plays a role in the formation of mutant huntingtin (Htt) aggregates in yeast [Source:SGD;Acc:S000004409]

GRD12, VAC3, VPL11

Chromosome XII: 955,010-956,710 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 346 orthologues and is a member of 1 Ensembl protein family.

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