TLC1 RNA-associated factor involved in telomere length regulation; recruitment subunit of telomerase; has G-quadruplex promoting activity required for telomere elongation; role in activating telomere-bound Est2p-TLC1-RNA; EST1 has a paralog, EBS1, that arose from the whole genome duplication [Source:SGD;Acc:S000004223]
Chromosome XII: 607,425-609,524 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 26 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
EST1 | YLR233C_mRNA | 2100 | 699aa | YLR233C | Protein coding | P17214 | - | Ensembl Canonical, |