DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant [Source:SGD;Acc:S000004022]

REV2, SNM2

Chromosome XII: 204,991-208,500 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 120 orthologues, 16 paralogues and is a member of 1 Ensembl protein family.

Show transcript tableHide transcript table