Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE16 has a paralog, ADE17, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine [Source:SGD;Acc:S000004018]

Chromosome XII: 199,540-201,315 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 344 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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