Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; during oxidative stress exports spermine, spermidine from the cell, which controls timing of expression of stress-responsive genes; phosphorylation enhances activity and sorting to the plasma membrane [Source:SGD;Acc:S000003951]

Chromosome XII: 84,804-86,564 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 377 orthologues, 9 paralogues and is a member of 1 Ensembl protein family.

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