Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; during oxidative stress exports spermine, spermidine from the cell, which controls timing of expression of stress-responsive genes; phosphorylation enhances activity and sorting to the plasma membrane [Source:SGD;Acc:S000003951]
Chromosome XII: 84,804-86,564 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 377 orthologues and 9 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TPO1 | YLL028W_mRNA | 1761 | 586aa | YLL028W | Protein coding | Q07824 | - | Ensembl Canonical, |