Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy [Source:SGD;Acc:S000003924]
Chromosome XII: 147,890-150,163 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 369 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
DNM1 | YLL001W_mRNA | 2274 | 757aa | YLL001W | Protein coding | P54861 | - | Ensembl Canonical, |