Essential conserved subunit of CPF cleavage and polyadenylation factor; plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA; contains a ubiquitin-like (UBL) domain, a RNA-binding zinc knuckle motif and a RING finger domain; both the zinc knuckle and RING finger are required for pre-mRNA binding; possible role in ubiquitination of Pap1p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001542]

Chromosome XI: 328,118-329,443 reverse strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 361 orthologues and is a member of 1 Ensembl protein family.

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