Subunit of chromosomal passenger complex (CPC); CPC is comprised of Ipl1p-Sli15p-Bir1p-Nbl1p and regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension; relative distribution to shortened microtubules increases upon DNA replication stress; sumoylated in an Mms21p-dependent manner; human survivin homolog [Source:SGD;Acc:S000003849]
Chromosome X: 587,718-590,582 forward strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 14 orthologues and is a member of 1 Ensembl protein family.