Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis; necessary for efficient targeting of Trm1p tRNA methyltransferase to inner nuclear membrane; mutations cause defects in cortical ER morphology in both the mother and daughter cells [Source:SGD;Acc:S000001352]
Chromosome IX: 193,595-195,070 forward strand.
R64-1-1:BK006942.2
This gene has 1 transcript (splice variant) and 311 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ICE2 | YIL090W_mRNA | 1476 | 491aa | YIL090W | Protein coding | P40499 | - | Ensembl Canonical, |