Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification; mutation also affects pseudouridylation of some nuclear-encoded mRNAs; PUS2 has a paralog, PUS1, that arose from the whole genome duplication [Source:SGD;Acc:S000003031]
Chromosome VII: 383,654-384,766 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 4 orthologues and 2 paralogues.