Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026]
PSO8, UBC2
Chromosome VII: 393,986-394,504 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 383 orthologues, 11 paralogues and is a member of 1 Ensembl protein family.