Aminolevulinate dehydratase; a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus; human homolog ALAD can complement yeast hem2 mutant [Source:SGD;Acc:S000003008]
OLE4, SLU1
Chromosome VII: 419,527-420,555 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 361 orthologues and is a member of 1 Ensembl protein family.