Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated [Source:SGD;Acc:S000002971]

HCT1

Chromosome VII: 492,474-494,174 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 361 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

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