F-box protein required for both the G1/S and G2/M phase transitions; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCFCdc4 complex; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates, such as: Sic1p, Far1p, Cdc6p, Clb6p, and Cln3p [Source:SGD;Acc:S000001885]
Chromosome VI: 116,145-118,484 forward strand.
R64-1-1:BK006940.2
This gene has 1 transcript (splice variant), 406 orthologues, 5 paralogues and is a member of 1 Ensembl protein family.