5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS2 has a paralog, PRS4, that arose from the whole genome duplication [Source:SGD;Acc:S000000901]
Chromosome V: 358,105-359,061 reverse strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant), 377 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.