Evolutionarily conserved kinetochore protein; part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002736]
CBF3D, MGO1
Chromosome IV: 1,125,434-1,126,018 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 381 orthologues and is a member of 1 Ensembl protein family.