Negative regulator of the glucose-sensing signal transduction pathway; required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation; MTH1 has a paralog, STD1, that arose from the whole genome duplication [Source:SGD;Acc:S000002685]

BPC1, DGT1, HTR1

Chromosome IV: 1,014,401-1,015,702 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 34 orthologues and 1 paralogue.

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