Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at late step of Fe-S cluster assembly; forms CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation into subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, telomere maintenance; contains WD40 repeats; human homolog CIAO1 can complement yeast cia1 null mutant [Source:SGD;Acc:S000002675]
Chromosome IV: 1,002,510-1,003,502 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 342 orthologues and is a member of 2 Ensembl protein families.