Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of SEACAT, a subcomplex of the SEA complex; Mtc1p, along with Rtc1p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; relative distribution to the vacuolar membrane decreases upon DNA replication stress [Source:SGD;Acc:S000002535]

Gene Synonyms

SEA3

Location

Chromosome IV: 709,549-712,995 forward strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 445 orthologues, 6 paralogues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MTC5YDR128W_mRNA34471148aaYDR128W
 
Protein coding
Q03897 -Ensembl Canonical