Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000002525]
Chromosome IV: 685,882-687,840 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 14 orthologues and is a member of 1 Ensembl protein family.