Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1 [Source:SGD;Acc:S000002490]
Chromosome IV: 612,073-613,251 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 351 orthologues and is a member of 1 Ensembl protein family.