Subunit of the HOPS endocytic tethering complex; vacuole membrane protein that functions as a Rab GTPase effector, interacting specifically with the GTP-bound conformation of Ypt7p, facilitating tethering, docking and promoting membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; Yck3p-mediated phosphorylation regulates the organization of vacuolar fusion sites [Source:SGD;Acc:S000002487]

CVT8, FET2, SVL2, VAM2, VPL20

Chromosome IV: 604,008-606,986 forward strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 357 orthologues and is a member of 1 Ensembl protein family.

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