Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466]
Chromosome IV: 569,234-569,770 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 98 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.