Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466]

Chromosome IV: 569,234-569,770 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 98 orthologues and 1 paralogue.

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