Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog FXN is mutated in Friedrich's ataxia; human FTL gene can complement yeast yfh1 null mutant [Source:SGD;Acc:S000002278]
Chromosome IV: 245,923-246,447 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 344 orthologues and is a member of 1 Ensembl protein family.