Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]
Chromosome IV: 417,663-421,514 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 332 orthologues, 6 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
OSH2 | YDL019C_mRNA | 3852 | 1283aa | YDL019C | Protein coding | Q12451 | - | Ensembl Canonical, |