Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p [Source:SGD;Acc:S000000264]
RRR1, SIR5
Chromosome II: 360,652-362,514 reverse strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant) and 345 orthologues.