Component of autophagosomes and Cvt vesicles; regulator of Atg1p, targets it to autophagosomes; binds the Atg1p-Atg13p complex, triggering its vacuolar degradation; unique ubiquitin-like protein whose conjugation target is lipid phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation; deconjugation of Atg8p-PE is required for efficient autophagosome biogenesis [Source:SGD;Acc:S000000174]
APG8, AUT7, CVT5
Chromosome II: 80,378-80,731 reverse strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 332 orthologues and is a member of 1 Ensembl protein family.